The Study for Follow Up Human Chorionic Gonadotropin (HCG) Levels and Gestational Trophoblastic diseases in Women With Molar Pregnancy in Uttaradit Hospital
Abstract
Objective : The purpose of this study to follow up human chorionic gonadotropin (HCG) levels and gestational trophoblastic diseases in women with molar pregnancy in Uttaradit Hospital.
Mothod : This is a retrospective study of cases of hydatidiform moles seen from 1 September 2003 to 31 October 2005 in Utaradit Hospital. Cases were identified through the records of names with the pathological diagnosis of hydatidiform mole, in Uttaradit hospital. The case records were then retrieved from the Medical Records Office and the data analysed. A total of 20 patients were studied.
Result : Twenty molar pregnancies were eligible for study. The maximum number of cases (35%) were found to be in the age group 20 - 24 years. In 7 cases (35%) the first pregnancy was molar, 7 cases (35%) first presented in the 10 - 15 weeks of pregnancy. In 18 case (90%) were found bleeding per vagina, was the most charecteristic symptom, 4 case (20%) has anemia, 2 cases (10%) has a uterine height more than the period of amenorrhoea and 2 case (10%) has abnormal thyroid hormone. Twelve patients were complete mole, 8 case (40%) were partial. Management was suction curettage in 19 cases (95%) and subtotal hysterectomy in one case (5%). Four patients with complete mole required chemotherapy. After molar evacuation, patients were advised to have serumHCG values measured weekly until undetectable for 2 times then monthly until undetectable and then every 2 month for one years. All case require careful HCG follow-upafter suction curettage, 16 case (80%) were completion of their full follow-up. The time intervalfrom suction curettage to achievement of the rapid normal HCG levelwas 4 weeks. However 3 case (15%) has increased HCG level was 4-12 weeks. Two of the complete mole found to have Gestational trophoblastic disease stage I.
Key word : Molar pregnancy, Follow up.
