Coagulopathy and Hematological Parameters of COVID-19 Patients Admitted in Lampang Hospital

Abstract

Abstract

            COVID-19 is an infectious disease caused by the SARS-CoV-2 virus that causes changes in the blood system.
The objectives of the study were to analyze laboratory results about coagulopathy and hematological parameters of patients admitted in Lampang Hospital according to the severity of the patient's symptoms. It was a retrospective study collecting data on COVID-19 patients with 3 levels of severity: moderate ill, semi critical ill and critical ill from 1 January 2020 - 31 May 2022 using the results of coagulopathy and hematological parameters for statistical analysis. Coagulopathy results which consisted of Prothrombin Time (PT), Activated Prothrombin Thromboplastin Time (aPTT), D-dimer values and Platelet count. The patients with all 3 levels of severity, the D-dimer values were significantly different (p=0.045) and hematological parameters showed that the white blood cell count were significantly different (p = 0.008) with increased in the early stage of infection. In this study the key markers for the severity and prognosis of COVID-19 patients are D-dimer values and white blood cell count.

Keywords : COVID-19, Coagulopathy, Hematological parameters