Neonatal outcome between INSURE method and conventional method in preterm infants with respiratory distress syndrome

Abstract

                                                                                                                Abstract

           Objective: To analyze neonatal outcomes between INSURE method and conventional method for surfactant administration in preterm infants with respiratory distress syndrome (RDS).

           Methods: A retrospective study was performed, including preterm infants with diagnosed RDS, who were admitted in NICU of Phatthalung hospital between 1^st January 2017 and 31th December 2019. Surfactant administration with INSURE method (n=59) and conventional method (n=65), were performed.

           Results: One-hundred and twenty-four infants were diagnosed with RDS. The mean birth weight and gestational age of infants were 1426  410 g and 30  2.7 weeks, respectively. The neonatal outcomes including ventilator day, oxygen day and length of hospital stay in INSURE group were significantly lower than conventional group.

           Conclusion: Surfactant administration with INSURE method can improve neonatal outcome and suitable to as an alternative initial treatment for preterm infants with respiratory distress syndrome.

Keywords: respiratory distress syndrome, surfactant, INSURE