Heat Stroke and The Other Heat Related Illness

Authors

  • Pattira Tantipasawasin Faculty of Medicine , Burapha university
  • Sittichai Tantipasawasin Chonburi hospital

Abstract

Climate change is causing global average temperatures to rise. The earth experiences extreme warming more often and over longer periods of time. As a result, the incidence of illness related to hot weather has increased. Hot-related illness is a disorder caused by an imbalance of thermoregulation mechanisms when the body is in a very thermal environment. They can be classified in order of mild to high severity: heat rash, heat edema, heat cramps, heat syncope,  rhadomyosis,  heat exhsustion, and heat stroke. 

Heat Rash

Hot or sweaty, characterized by small bumps on the skin. Caused by irritation of the skin. When the skin sweats a lot during hot weather, especially in hot and humid environments. The air has high relative humidity, causing the sweat gland ducts to become clogged. It is commonly found in the neck, chest, under the breast rail, armpits, groin, and other crooks of the arms and legs. Prevention of heat or sweating is achieved by trying to work in a cold environment. Low relative humidity Keep the location of the rash easily dry. Avoid applying creams or oils to the skin.

Heat edema

Sun swelling is a less severe heat-related illness. Symptoms are characterized by swelling and stiffness of the hands and feet. It is caused by the expansion of blood vessels in the skin area and fluid retention in the space between the cells in the arms and legs from sitting or standing for long periods of time. Swelling and stiffness in the feet may swell up to the ankles. Most do not swell above the shin and occur in the first few days of hot weather, especially in those who have not acclimatized to the hot weather. Sun swelling improves with avoiding prolonged sitting or standing. Do physical exercises, stretch arms and legs periodically.

Heat Cramps

Cramps are spontaneous muscle spasms that are not derived from the original underlying disease. It is usually found in athletes, workers who have to work hard or exercise for long periods of time. In hot weather, it causes a lot of sweating. The body loses a lot of water and minerals. This causes a decrease in the amount of mineral salts in the muscles. The main minerals are magnesium and potassium. It occurs more often in the muscles of the abdomen. Cramps can be caused by drinking a lot of cold water quickly after an activity, leading to extreme fatigue. In extreme heat. Cramps are an important warning sign before sun exhaustion.

Heat Syncope

Heatstroke is one of the most common symptoms when you are active in the sun for long periods of time. Symptoms include dizziness. Awareness of balance and place changes, feeling like head spinning. Fainting, temporary fainting due to a sudden drop in blood pressure after changing from a lying or sitting position to a rapid standing position. When in the sun for long periods of time. Causes of dilation of blood vessels in the skin This causes a decrease in the relative blood volume in the circulatory system. As a result, the amount of blood pumped to the brain is insufficient. The main factors that cause heat stroke are dehydration, lack of preparation to adjust to the body before outdoor activities, and gradually reducing fatigue from exercise.

Acute decay muscle stribe (rhadomyosis)

The occurrence of acute disintegration of striated muscles from activity. Prolonged extreme heat is a rare condition in general practice. Symptoms of acute striated muscle breakdown include: Muscle pain, cramps, muscle weakness, decreased endurance Many electrolytes, proteins, and other compounds inside the decay cells are released into the bloodstream. This results in irregular heartbeat, seizures, and damage to the kidneys, causing kidney damage. Serum keatinin phosphokinase levels  are significantly elevated. Myogolbin urea, muscle myogolbin protein found in urine. The urine is black like Coca Cola water. First aid to stop all activities in progress. Drink plenty of water. and take to the hospital for medical treatment.

 Heat exhaustion

Sun exhaustion is a symptom of exhaustion that occurs as a result of exposure to extremely hot air and high relative humidity. This causes the body to lose a lot of water and minerals from sweating a lot while doing strenuous activities or exercise. Causes dehydration and electrolyte depletion The heart pumps blood to organs decreases. It is more common in the elderly. Patients with high blood pressure and workers working outdoors or in hot weather. As a result, the core temperature rises above 38  degrees Celsius (100.4°F) but not more than 40.5 degrees Celsius (104.9°F) without any abnormalities in the functioning of the body's temperature-controlled nervous system. Symptoms of sun exhaustion include headache, nausea, dizziness. Weakness, restlessness, thirst, excessive sweating, less urination Rapid heartbeat may cause cramps and dehydration.

Heat Stroke

Heat stroke, or heat stroke, is the most intense heat-related illness. It is a condition in which the core temperature rises rapidly, exceeding 40.5 degrees Celsius within 10-15 minutes. Due to the body's inability to maintain the heat balance to the normal core temperature. This is due to a failure of the cooling mechanism. adversely affects the nervous system, Heat stroke can cause permanent disability or death. If not treated in a timely manner. Signs  and symptoms of heatstroke include axial temperature above 40.5 degrees Celsius, which is the main symptom of heat stroke. Changes in level of consciousness or behavior,  such as confusion, restlessness, slurred speech, hard tongue, irritability, delirium, seizures, and insensitivity. Sweating changes. Normally, in hot weather, sweating is intense, but in heatstroke patients, the skin feels hot but dry, or just a little damp. Nausea and vomiting, red skin, rapid but shallow breathing Rapid heartbeat, headache

Conclusion Extreme heat is a silent threat that poses a fatal summer hazard. Heatstroke is a medical emergency, but it can be corrected if it is treated in a timely manner. A healthy cardiovascular system is critical to maintaining balance between heat and core temperature. People with underlying diseases of the cardiovascular system, especially the elderly. Increased risk of heatstroke Heatstroke results in multi-organ system failure. In very severe cases, heart failure may occur. Circulatory system failure and subsequent death. Cooling, temperature reduction and palliative care It is very important to maintain heat stroke. Prevention is still more important than treatment. Risk Factor Awareness Preparing and acclimatizing the body and avoiding activities during periods of extreme heat can help reduce the incidence of heat-related illness.

Author Biographies

Pattira Tantipasawasin, Faculty of Medicine , Burapha university

Maxillofacial Surgery

Sittichai Tantipasawasin, Chonburi hospital

chairman of oral and maxillofacial surgery department

References

BARROW WM, CLARK AK. Heat-Related Illnesses. Am Fam Physician.1998; 58(3):749-56.

Yankelson L, Sadeh B, Gershovitz L. Life-threatening events during endurance sports: is heat stroke more prevalent than arrhythmic death? J Am Coll Cardiol 2014; 64:463–9.

Centers for Disease Control and Prevention HEAT STRESS

https://www.cdc.gov/niosh/topics/heatstress/default.html

Shimazaki. Pathogenesis of heat stroke. 2nd ed. Tokyo: Health; 2017.

Bouchama A, Knochel.PJ. Heat Stroke. N Engl J Med. 2002; 346(25):1978-88. https://www.nejm.org/doi/10.1056/NEJMra011089?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed. doi: 10.1056/NEJMra011089.

Epstein Y, Yanovich R. Heat stroke. N Engl J Med 2019; 380:2449-59.

Hifumi T, Kondo Y, Shimizu K, Miyake Y. Heat stroke. J Intensive Care 2018; 22 (6):30.https://pubmed.ncbi.nlm.nih.gov/29850022/ doi: 10.1186/s40560-018-0298-4.eCollection 2018.

Hifumi T, Kondo Y, Shimazaki J, Oda Y, Shiraishi S, Wakasugi M,et al. Prognostic significance of disseminated intravascular coagulation in patients with heat stroke in a nationwide registry. J Crit Care. 2017; 44:306–11.

Kushimoto S, Yamanouchi S, Endo T, Sato T, Nomura R, Fujita M, et al. Body temperature abnormalities in non-neurological critically ill patients: a review of the literature. J Intensive Care. 2014; 2:14.

Miyake Y. Pathophysiology of heat illness: thermoregulation, risk factors, and indicators of aggravation. Japan Med Assoc J. 2013; 56:167–73.

Leon LR, Helwig BG. Heat stroke: role of the systemic inflammatory response. J Appl Physiol 2010;109:1980-8.

Lim CL, Mackinnon LT. The roles of exercise-induced immune system disturbances in the pathology of heat stroke: the dual pathway model of heat stroke. Sports Med. 2006; 36:39–64.

Huisse MG, Pease S, Hurtado-Nedelec M, Arnaud B, Malaquin C, Wolff M, et al. Leukocyte activation: the link between inflammation and coagulation during heatstroke. A study of patients during the 2003 heat wave in Paris. Crit Care Med. 2008; 36:2288–95.

Tong HS, Tang YQ, Chen Y, Qiu JM, Wen Q, Su L. Early elevated HMGB1 level predicting the outcome in exertional heatstroke. J Trauma. 2011; 71:808–14.

Deschamps A, Levy RD, Cosio MG, Marliss EB, Magder S. Effect of saline infusion on body temperature and endurance during heavy exercise. J Appl Physiol. 1989; 66:2799–804. https://pubmed.ncbi.nlm.nih.gov/2745343/ doi: 10.1152/jappl.1989.66.6.2799

Hassanein T, Razack A, Gavaler J, Van Thiel DH. Heatstroke: its clinical and pathological presentation with particular attention to the liver. Am J Gastroenterol.1992;87:1382-9.

Bross MH, Nash BT, Carlton FB. Heat emergencies. Am Fam Physician. 1994; 50:389-96.

Minson CT, Wladkowski SL, Cardell AF, Pawelczyk JA, Kenney WL. Age alters the cardiovascular response to direct passive heating. J Appl Physiol. 1998; 84:1323-32.

Miles M, Kenneth G. The Cardiovascular System in Heat Stroke. CJC Open 2021;4(2):158-63. https://www.cjcopen.ca/article/S2589-790X(21)00271-7/fulltext p 158-63. doi: 10.1016/j.cjco.2021.10.002

Bouchama A, Dehbi M, Mohamed G, et al. Prognostic factors in heat wave related deaths: a meta-analysis. Arch Intern Med. 2007; 167:2170-6.

Wang J-C, Chien W-C, ChuID P, Chung C-H, Lin CY, TsaiID S-H The association between heat stroke and subsequent cardiovascular diseases. PLOS ONE. 2019; 14(2): e0211386. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211386. doi:/10.1371/journal.pone.0211386

Kenney WL, Morgan AL, Farquhar WB, et al. Decreased active vasodilator sensitivity in aged skin. Am J Physiol 1997; 272(4 Pt 2): H1609-14.

Berenson GS, Burch GE. The response of patients with congestive heart failure to a rapid elevation in atmospheric temperature and humidity. Am J Med Sci 1952;223:45-53.

Bathini T, Thongprayoon C, Petnak T. Circulatory failure among hospitalizations for heatstroke in the United States. Medicines (Basel). 2020; 7:32.

Akhtar MJ, al-Nozha M, al-Harthi S, Nouh MS. Elecเtrocardiographic abnormalities in patients with heat stroke. Chest 1993; 104:411-4.

Mimish L. Electrocardiographic findings in heat stroke and exhaustion: a study on Makkah pilgrims. J Saudi Heart Assoc 2012; 24:35-9.

al-Harthi SS, Nouh MS, al-Arfaj H, et al. Non-invasive evaluation of cardiac abnormalities in heat stroke pilgrims. Int J Cardiol 1992; 37:151-4.

Pease S, Bouadma L, Kermarrec N, et al. Early organ dysfunction course, cooling time and outcome in classic heatstroke. Intensive Care Med 2009; 35:1454-8.

Hausfater P, Doumenc B, Chopin S, et al. Elevation of cardiac troponin I during non-exertional heat-related illnesses in the context of a heatwave. Crit Care 2010; 14: R99.

Chen WT, Lin CH, Hsieh MH, Huang CY, Yeh JS. Stress-induced cardiomyopathy caused by heat stroke. Ann Emerg Med. 2012; 60: 63-6.

Sprung CL. Hemodynamic alterations of heat stroke in the elderly. Chest 1979; 75:362-6.

Kaiser R, Le Tertre A, Schwartz J, et al. The effect of the 1995 heat wave in Chicago on all-cause and cause-specific mortality. Am J Public Health 2007;97(suppl 1): S158-62.

Tan W, Herzlich BC, Funaro R, Koutelos K, Pagala M, Amaladevi B, et al. Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke. South Med J. 1995; 88:1065-8.

Smith JE. Cooling methods used in the treatment of exertional heat illness. Br J Sports Med 2005, 39:503-7

Casa DJ, McDermott BP, Lee EC, et al. Cold water immersion: the gold standard for exertional heatstroke treatment. Exerc Sport Sci Rev. 2007; 35:141-9.

Costrini A. Emergency treatment of exertional heatstroke and comparison of whole body cooling techniques.Med Sci Sports Exerc.1990;22:15-8.

Roberts WO. Managing heatstroke: on-site cooling. Physician Sports med. 1992;20:17-28.

Lee-Chiong TL, Stitt JT. Heatstroke and other heat-related illnesses. The maladies of summer. Postgrad Med. 1995; 98:26-36.

Bross MH, Nash BT, Carlton FB. Heat emergencies. Am Fam Physician.1994; 50:389-96.

Broessner G, Beer R, Franz G, Lackner P, Engelhard K, Brenneis C, et al. Case report: severe heat stroke with multiple organ dysfunction – a novel intravascular treatment approach. Crit Care 2005; 9: R498-R5.

Schmutzhard E, Engelhardt K, Beer R, Brossner G, Pfausler B, Spiss H, et al. Safety and efficacy of a novel intravascular cooling device to control body temperature in neurologic intensive care patients: a prospective pilot study. Crit Care Med. 2002; 30:2481-8

Marion DW: Controlled normothermia in neurologic intensive care. Crit Care Med 2004, 32:S43-S45

Diringer MN. Treatment of fever in the neurologic intensive care unit with a catheter-based heat exchange system. Crit Care Med. 2004; 32:559-564

Walker JS, Hogan DE: Heat emergencies. In Emergency Medicine: A Comprehensive Study Guide, Section 15. Edited by Tintinalli JE, Kelen GD, Stapczynski S. American College of Emergency Physicians. 2004:1183-1189

Tek D, Olshaker JS. Heat illness. Emerg Med Clin North Am 1992;10: 299-310.

Rublee C, Dresser C, Giudice C, Lemery J, Cecilia So. Evidence-Based Heatstroke Management in the Emergency Department Western Journal of Emergency Medicine. 2021; 22(2): p 186-95. http://escholarship.org/uc/uciem_westjem DOI: 10.5811/westjem.2020.11.49007

Alzeer AH, el-Hazmi MA, Warsy AS, Ansari ZA, Yrkendi MS. Serum enzymes in heat stroke: prognostic implication. Clin Chem. 1997;43:1182-7.

Nylen ES, Al Arifi A, Becker KL, Snider RH, Alzeer A. Effect of classic heatstroke on procalcitonin. Crit Care Med. 1997;25:1362-5

Epstein Y, Sohar E, Shapiro Y. Exertional heatstroke: a preventable condition. Isr J Med Sci.1995; 31:454-62.

Roberts WO. Determining a “do not start” temperature for a marathon on the basis of adverse outcomes. Med Sci Sports Exerc 2010; 42: 226–32.

Kim JH, Malhotra R, Chiampas G, et al. Cardiac arrest during long-distance running races. N Engl J Med 2012; 366:130–40.

Armstrong LE, Epstein Y, Greenleaf JE, Haymes EM, Hubbard RW, Roberts WO, et al. American College of Sports Medicine position stand. Heat and cold illnesses during distance running. Med Sci Sports Exerc 1996; 28: i–x.

Tek D, Olshaker JS. Heat illness. Emerg Med Clin North Am.1992; 10:299-310.

Squire DL. Heat illness. Fluid and electrolyte issues for pediatric and adolescent athletes. Pediatr Clin North Am. 1990; 37:1085-109.

Dehbi M, Baturcam E, Eldali A, et al. Hsp-72, a candidate prognostic indicator of heatstroke. Cell Stress Chaperones 2010; 15:593-603.

Tsai YC, Lam KK, Peng YJ, Lee YM, Yang CY, Tsai YJ, Yen MH, Cheng PY. Heat shock protein 70 and AMP-activated protein kinase contribute to 17- DMAG-dependent protection against heat stroke. J Cell Mol Med. 2016;20: 1889–97.

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Published

2023-06-01 — Updated on 2023-07-04

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