Colorectal Cancer Screening by Fecal Immunochemical Testing with Colonoscopy in Chonburi province

Abstract

Colorectal cancer (CRC) is one of the major health problems in Thailand and there is increasing in colorectal cancer incidence annually nationwide. The present descriptive study aimed to investigate and detect patients with early stage of colorectal cancer. Factors associated with CRC in patients living in Chonburi province are investigated and analyzed. Data of 4,257 patients were collected retrospectively during January-December 2017. Recorded patient data including family history of CRC, health behaviors, patient signs that may be associated with CRC and CRC screening and confirmatory tests. Descriptive statistics including percentage, mean, standard deviation and Inferential statistics including Chi-square test and Multiple logistic regression were analyzed.

The results showed that 319 of 4,257 (7.5%) were positive for fecal immunochemical test (FIT). 157 patients were confirmed by colonoscopy. 38 of whom had neoplasm (24.2%). All the neoplasm were adenoma (19 cases), advanced adenoma (10 cases) and colorectal cancer (9 cases; 5.7%). Analyzed risk factors associated with neoplasm in the present study including heavy alcohol use, mucus or blood in the stool, constipation and frequent abdominal cramps. Screening of colorectal cancer annually using combined tests, FIT and colonoscope would help for early detection of CRC lesions and treatment can be immediate performed to decrease the incidence of mortality.