Fatal Avian Influenza: A Case Report in Nong Bua Lam Phu Hospital

Abstract

A case report of a 59 years- old, Thai man came to hospital with high fever, fatique, headache about 10 day without respiratory symptoms.  He had history of contact with dying poultry 4 days before becoming ill.

Physical exammination: high fever,crepitation sound at both basal lung field CXR : Bilateral alveolar infiltration, RT-PCR from endotracheal suction, not found H5N1 virus.  The doctor treated with tamiflu and antibiotic for cover bacterial pneumonia.  But the patient had not improved,and then he had respiratrory failure and died.  In an autopsy that followed, diffuse alveolar damage and pulmonary hemorrhage were reported, H5N1 virus were identified in stool and lung by RT-PCR in a laboratory investigation.