Prevalence and Associated factors of I-sarn Syndrome among the Diabetic Patients and Hypertensive Patients in Rural Communities,Public Health Region 7, Thailand
Keywords:
I-sarn syndrome, Type 2 Diabetes, Hypertension, กลุ่มอาการอีสานรวมมิตร, โรคเบาหวาน, โรคความดันโลหิตสูงAbstract
Background and objectives: I-sarn syndrome (ISS) is one of the important health issues that is common among diabetic (T2DM) and hypertensive (HT) patients in the Northeast of Thailand. It has been shown that ISS is related to small renal stones, chronic pyelonephritis and chronic kidney disease. The purposes of this study were to determine the prevalence of ISS and their associated factors among the diabetic and hypertensive patients in rural communities.
Methods: A retrospective cohort study, using patients’ data from Ubonratana hospital’s pilot project in 13 rural sub-districts in public health region 7was conducted. Altogether, 3,332 T2DM and HT patients, aged 20 to 80 years were interviewed during January 2016 - September 2016. Instruments were used as the following: 1) questionnaire for demographic data 2) questionnaire for physical health, health behaviors 3) Laboratory examination: GFR, HbA1C and Urinalysis. Data analysis was conducted by frequency, percentage, prevalence rate with 95% CI, Pearson’s chi square test, odds ratio and multiple logistic regression.
Results: Most of the participants were farmers (77.7%), 29.3% were males, 56.6% were older than 60 years. Age-gender adjusted prevalence of ISS was 32.5% (95%CI: 30.9 - 34.1). The associated factors of ISS were the consumption of bamboo shoot & fermented rice noodle (adjusted OR = 2.1, 95% CI: 1.4-3.1), consumption foods containing monosodium glutamate (MSG) (adjusted OR = 1.9, 95% CI: 1.1-3.3), decreased glomerular filtration rate (GFR) < 60 ml/min/1.73 m2 (adjusted OR = 2.5, 95% CI: 1.6-3.9), albuminuria (adjusted OR = 1.7, 95% CI: 1.1-2.4) and history of urine with sediment (adjusted OR = 2.8, 95% CI: 1.9-4.2)
Conclusion: The study revealed that one third of the T2DM and HT patients had ISS and significantly related to consumption of bamboo shoot & fermented rice, consumption foods containing MSG, decreased GFR, albuminuria and history of urine with sediment.
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