The Post-stroke depression in older adults
Abstract
Stroke is one of the leading causes of death in older adults. Over one-third of stroke patients experience depression. Most stroke survivors are found Post-stroke depression (PSD) within one year after stroke. The common clinical manifestations of PSD in older adults are frustration, fatigue, and loss of interest in activities which have negative impact on response to rehabilitation. Moreover, PSD contributes to reduced quality of life and increased hospitalization, morbidity and mortality. Pathophysiology of PSD consists of neurobiological and psychological factors. PSD is usually diagnosed by comprehensive taking histories and appropriate depression assessment tools. Both psychosocial and pharmacological treatment play major roles in reduced PSD. Selective serotonin reuptake inhibitors have been approved for treatment PSD in older adults. Therefore, we aimed to update the diverse aspects of PSD in older adults population such as epidemiology, pathophysiology, clinical manifestations, diagnosis and treatment
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