Flagellate Erythema in a Patient with Adult-Onset Still’s Disease: A Case Report
Keywords:
Flagellate Erythema, Adult-onset Still’s diseaseAbstract
Adult-onset Still’s disease is a rare systemic inflammatory disorder. Clinical manifestations and symptoms may vary among individuals, making it difficult to diagnose this disease from an early stage and cause delays in treatment. In most cases, patients may develop episodes of high fevers together with a pinkish-orange maculopapular rash on trunk and extremities, which usually disappears when the fever subsides. Other severe symptoms of adult-onset Still’s disease include pleuritis, myopericarditis, interstitial lung disease, and reactive hemophagocytic syndrome. This report shows an example of an affected patient with flagellate erythema. Although this skin sign is atypical symptom, it is considered relatively relevant to adult-onset Still’s disease. The patient was diagnosed and received a proper medical treatment in a timely manner and could be discharged from hospital eventually.
References
Efthimiou P, Georgy S. Pathogenesis and man-agement of adult-onset Still’s disease. Seminars in arthritis and rheumatism 2006;36(3):144-52.
Bhargava J, Panginikkod S. Still disease. Treasure Island (FL): StatPearls Publishing; 2020.
Piette WW. Rheumatoid arthritis, rheumatic fever, and gout. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffel DJ, Wolff K, editors. Fitzpatrick’s dermatology in general medicine. 8th ed. New York: McGraw-Hill Medical; 2012. p. 1965-76.
Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, et al. Preliminary criteria for classification of adult Still’s disease. The Journal of rheumatology 1992;19(3):424-30.
Lee LA, Werth VP. The skin and rheumatic diseases.In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O’Dell JR, editors. Kelley’s textbook of rheumatology.9th ed. Philadelphia: W.B. Saunders; 2013. p. 599-616.
Qiao J, Pan Y, Li S, Tang S, Zheng S, Zhu D, et al. Adult-onset Still disease presenting with dermatomy-ositis-like persistent pruritic lesions. The AmericanJournal of dermatopathology 2019;41(11):851-4.
Fernandez-Obregon AC, Hogan KP, Bibro MK. Flagellate pigmentation from intrapleural bleomycin.A light microscopy and electron microscopy study.Journal of the American Academy of Dermatology 1985;13(3):464-8.
Hanada K, Hashimoto I. Flagellate mushroom (Shi-itake) dermatitis and photosensitivity. Dermatology (Basel, Switzerland) 1998;197(3):255-7.
Kaur S, Bambery P, Dhar S. Persistent dermalplaque lesions in adult onset Still’s disease. Der-matology (Basel, Switzerland) 1994;188(3):241-2.
Ciliberto H, Kumar MG, Musiek A. Flagellate ery-thema in a patient with fever. JAMA dermatology 2013;149(12):1425-6.
Suzuki K, Kimura Y, Aoki M, Takezaki S, Tuchida T, Takano T, et al. Persistent plaques and linear pigmentation in adult-onset Still’s disease. Derma-tology (Basel, Switzerland) 2001;202(4):333-5.
Lee JY, Yang CC, Hsu MM. Histopathology of persistent papules and plaques in adult-onsetStill’s disease. Journal of the American Academy of Dermatology 2005;52(6):1003-8.
Qiao J, Zhou S, Li S, Xue R, Pan Y, Tang S, et al. Histopathological diagnosis of persistent pruritic eruptions associated with adult-onset Still’s disease.Histopathology 2019;74(5):759-65.
Rosário C, Zandman-Goddard G, Meyron-HoltzEG, D’Cruz DP, Shoenfeld Y. The hyperferritinemic syndrome: macrophage activation syndrome, Still’s disease, septic shock and catastrophic antiphos-pholipid syndrome. BMC medicine 2013;11:185. doi: 10.1186/1741-7015-11-185.
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