Factors Associated with In-hospital Mortality in Patients with Intracerebral Hemorrhage at Ban-Mi Hos-pital, Lopburi Province, Thailand

Abstract

The objective of this study was to analyse the various factors affecting the mortality of patients with intracerebral hemorrhage (ICH) after conservative treatment. It was conducted as a retrospective analytic study by collecting data from medical records of ICH patients who were admitted to Ban-Mi hospital, Lopburi Province during October 2013 - September 2015. A total of 125 redical records were included. It was found that the most frequent risk factors were hypertension (68.0%) and diabetes mellitus (17.6%). The most frequent localization of ICH was basal ganglia (36.0%), and multiple site (23.2%). The highest mortality rate was in the patients with multiple site (89.7%). The overall mortality rate among ICH patients admitted to the hospital was 59.2%. About one half of the deaths occured within the first two days after brain injury. Factors associated with mortality were Glasgow coma scale (GCS) both at emergency room and at admission ward, midline shift, intraventricular extention, hydrocephalus, multiple site, and length of stay. After adjusted multivariated analysis we found that GCS <8 both at ward admission and emergency room, diabetes mellitus, intraventricular extention were independent factors associated with mortality. The odds ratio and 95%CI for these factors were 24.23 (5.38-109.06; p=<0.001) , 18.64 (2.18-123.30; p=0.002) , 9.56 (1.60-57.08; p=0.013), and 5.46 (1.04-28.63; p=0.045) , re-spectively.