Clinical Manifestation of Clear Cell Hidradenoma at Neck: a Rare Case of Tumor of Duct Origin of Sweat Gland

Abstract

Clear cell hidradenoma is a rare benign tumor of skin and reports of clinical manifestation are quite limited. We report a 35-year-old Thai male who presented at Buddhasothorn Hospital, Chachoengsao Province, with recurrent tumor on the neck. The patient was treat with total surgical removal of the tumor. Pathological studies showed that the intradermal tumor cell was composed of 2 cell populations, polygonal-shaped clear cells and round cells. Small ductal structures were rarely seen. Mitotic features were not identified. The tumor was partially stained with EMA. CEA failed to highlight the ductal component. The stains for S-100, Ber-EP4, RCC and CD34 were negative. These results were consistent with clear cell hidradenoma. The patient was not given any postoperative adjuvant treatment. No recurrence was detected at a follow-up visit 5 months after the operation.