Genetic Amniocentesis at Chachoengsao Hospital - การเจาะน้ำคร่ำเพื่อการวินิจฉัยทางพันธุกรรม ที่โรงพยาบาลเมืองฉะเชิงเทรา

Abstract

                A total of 391 pregnant women with high risk of fetal chromosomal abnormalities underwent genetic amniocentesis at Chachoengsao hospital from September 2001 to December 2007.  The most common indication for amniocentesis was advanced maternal age (97.69%).  The success rate of cell-culture was 99.74 percent.  There were 2.05 percent (8/390) of abnormal chromosomes.  The abortion rate within four weeks after the procedure was 1.28 percent (5/390).  Pregnancy outcomes of those with normal fetuses included spontaneous abortions 0.66 percent (2/303) premature deliveries 9.9 percent (30/303), and term deliveries 89.44 percent (271/303).  It was concluded that amniocentesis did not cause any significant complication in these population.

Key words:      genetic amniocentesis, pregnancy outcome