Penile Cancer in Bhuddhachinaraj Hospital : Analysis of Prognostic Factors for Inguinal Node Metastasis

Abstract

Penile cancer is an uncommon disease. This retrospective descriptive study reported 102 patients who had penile cancer treated at Bhuddhachinaraj Phitsanulok Hospital from January 2001 to December 2011. The average age was 59.59 years. Most of clinical presentation included exophytic growth and ulcer. The surgical management for penile lesion included partial penectomy in 67.6 percent and total penectomy in 26.5 percent. The histological differentiation of tumor included well differentiated carcinoma in 52 percent, moderately differentiated carcinoma in 39.2 percent and poorly differentiated carcinoma in 6.9 percent. The patients had no clinical groin node metastasis in 52.9 percent and had groin node metastasis in 47.1 percent with average time after penile amputation was 3.56 months and the longest time in case of groin node metastasis after amputation was 15 months. The main factors affecting significantly the incidence of groin node metastasis was degree of tumor differentiation but age and T stage were not. Lymphatic and venous embolization were most likely suggestive factors affecting incidence of groin node metastasis. The patients who had significant incidence should undergo immediate inguinal lymphadenectomy.