Inpatients HIV Infection at Paholpolpayuhasaena Hospital in 2 Years-ผู้ป่วยติดเชื้อไวรัส เอชไอวีที่รับเป็นผู้ป่วยในของโรงพยาบาลพหลพลพยุหเสนาในระยะเวลา 2 ปี

Abstract

         HIV disease is the one of health problem inThailand.  Many HIV/AIDS patients are still suffering from opportunistic infection and HIV itself.  Although HIV/AIDS patients can easily access antiretroviral therapy, the morbidity and mortality were still stable.  The retrospective descriptive study was conducted by reviewing the medical records during January 1st 2006 - December 31st 2007.  The data from HIV/AIDS patients who admitted in medical ward were collected in order to determine the demographys, causes of disease and death, antiretroviral therapy and clinical outcomes. 

         There were 427 HIV/AIDS patients during study period, the mean age was 38.8 years and 58.3 percent were male, AIDS-defining illness was observed in 58.0 percent.  There were 35.5 percent of all patients newly diagnosed with HIV infection.  The three most common discharged diagnoses were tuberculosis (25.5%), Pneumocystis carinii pneumonia (13.6%) and Cryptococcal meningitis (12.9%).  Antiretroviral therapy had been given to 25.3 percent of all patients.  The patients who received antiretroviral therapy had significantly less tuberculosis and Pneumocystis carinii pneumonia than those without antiretroviral therapy.  The mortality among all HIV/AIDS patients was 24.6 percent and decreased significantly in HIV/AIDS patients who received antiretroviral therapy compared to those without antiretroviral therapy (12.9%, 28.5%; p = 0.002). 

           Early detection of HIV/AIDS, infection, screening in high risk groups, effective health care system easily access of antiretroviral therapy are the important strategies to reduce morbidity and mortality in HIV/AIDS patients.

Key words:   AIDS, HAART, HTV, cause of death, mortality, opportunistic infiections