The pre valence of Carbapenem Resistant Enterobacteriaceae in Mukdahan Hospital

Abstract

The carbapenem resistant Enterobacteriaceae (CRE) prevalence is increasing around the world. The CRE infection causes limitations in the treatment because it is resistant to many groups of drugs. Resulting in patients being at risk of complications and higher mortality. This study is a retrospective study. The objective of this study was to study the prevalence and trend of CRE isolated from patients who were admitted in Mukdahan Hospital during 2016-2018 as a guideline for a campaign to control anti-microbial resistance for better quality. Enterobacteriaceae of 3,663 cases, found that 1,289 cases were resistant to 3^rd cephalosporins and all CRE were 54 (1.5%). Studies show that CRE is increasing every year with 1.1, 1.5 and 1.8% respectively. The most CRE was found in the medical ward (2.4%) and most of the male (55%). They were most isolated from urine (2.3 %) and following isolated rate was from sputum (1.8 %), pus (1.2 %) and blood (1.0 %), respectively. K. pneumoniae infection were most CRE 2.5%, followed by Enterobacter spp., and E.coli 1.8% and 1.2% respectively. The CRE infection rate was increasing every years, therefore, it is very important that the hospital AMR surveillance working group should work together to assess review and restore knowledge of infection prevention and control to staff at all levels have common awareness. To solve the problem of drug resistance in hospitals to be effective.