The Clinical Characteristics of Geriatric Cancer Patients in Chonburi Hospital and Geriatric Assessment by G8

Authors

  • Annop Kittiwarawut Chonburi Hospital

Abstract

Background

The aging population continued to grow up, by 2022, about one-fifth of Thai population would be age 65 or older. New diagnosed cancer mostly affected older adults. A geriatric assessment-based might benefit older patients. G8 screening tool are practical and easy assessed for treatment-related toxicity. This study aimed to review the characteristic of geriatric cancer patients in Chonburi hospital and evaluate geriatric assessment by G8 tool.

Methods

A descriptive retrospective hospital-based study of non-hematologic cancer patients. Eligible patients were aged 65 years and older who received cancer treatment in Oncology department in Chonburi hospital. Geriatric assessment was done by using G8 screening tool.

Results

Total elderly cancer patients were 243 cases and the prevalence was 36% of total cancer patients treated during the study period. The mean age was 73.05 years, with the majority of patients being male (61.3%), mean body mass index (BMI) was 21.60, mean surface area (BSA) was 1.56 which 61.7% had BSA > 1.50. The most common was colon cancer (37.9%). followed by lung cancer (36.2%). The performance status was mainly ECOG1 (47.7%). Almost of the patients had other underlying medical conditions. Main are advanced stage (61.3%) and aims were palliation. Approach patient with G8 tool assessment found that the majority were frail group (78.2%). Factor which can reduce the likelihood of side effects from chemotherapy treatment was the G8 score. The fit group had statistically significantly less side effects than the frail group (p = 0.012). A negative correlation was found between G8 scores and reduction in chemotherapy dose, statistically significant (r = -0.26, p < 0.0001)

Conclusion

The prevalence of elderly cancer patients in Chonburi Hospital was 36% and main population were frail. The G8 tool was able to distinguish the fit and frail patient groups. Geriatric assessment-based intervention has a significantly fewer side effects from chemotherapy treatment in oncological cancer care.

Author Biography

Annop Kittiwarawut, Chonburi Hospital

อายุรแพทย์มะเร็งวิทยา กลุ่มงานอายุรกรรม

References

มูลนิธิสถาบันวิจัยและพัฒนาผู้สูงอายุไทย. รายงานสถานการณ์ผู้สูงอายุไทย ปี 2561 [อินเทอร์เน็ต]. 2019 [เข้าถึงเมื่อ 6 มิถุนายน 2563]. เข้าถึงได้จาก: https://thaitgri.org/?p=38670

สถาบันวิจัยประชากรและสังคม มหาวิทยาลัยมหิดล, 24 ตุลาคม 2562, www.ipsr.mahidol.ac.th

Data source United Nations, department of economic and social affaires population dynamics, world population prospects 2020, www.macrotrends.net

Smith BD, Smith GL, Hurria A, Hortobagyi GN, Buchholz TA. Buchholz, Future of cancer incidence in United States: burdens upon an aging, changing nation. J Clin Oncol. 2009;27(17):2758-65.

NCCN clinical practice guidelines in oncology, older adult oncology version 1, 2020, February 7, 2020.

Liuu E, Canouï-Poitrine F, Tournigand C, Laurent M, Caillet P, Le Thuaut A, et al.

Accuracy of the G-8 geriatric-oncology screening tool for identifying vulnerable elderly patients with cancer according to tumour site: the ELCAPA-02 study. J Geriatr Oncol. 2014;5(1):11-9.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009;59(4):225-49.

Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7-33.

Li Y, XU X, Dai M, Chen Y. Cancer in elderly in China: a nationwide population-based observational study. Cancer Communications. 2020;40(12):657-68.

Cheung KL, Chong MHM, Huang YJ, et al. Geriatric oncology in Singapore: current status and future directions. J Geriatr Oncol. 2020;11(1):1-7.

Hurria A, Mobile S, Gajra A, Klein H, Muss H, Chapman A, et al. Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol. 2016;34(20):2366-71.

Anido-Herranz U, Fernandez-Nunez N, Afonso-Afonso J, Santome-Coute L, Medina-Colmenero A, Fernandez-Calvo O, et al. Chemotherapy management for unfit patients with metastatic castration-resistant prostate cancer. Clin Transl Oncol. 2019;(3):249-58.

Droz JP, Balducci L, Bolla M, Emberton M, Fitzpatrick JM, Joaniau, et al. Managment of prostate cancer in older men: recommendations of a working group of the international society of geriatric oncology. BJU Int. 2010;106(4):462-9.

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Published

2023-04-30