Comparison of Anemia in Patients with Falciparum Malaria in Endemic Area Before and After Radical Treatment - การศึกษาเปรียบเทียบภาวะเลือดจางของผู้ป่วย P falciparum ในท้องที่แพร่เชื้อมาลาเรียก่อนและหลังได้รับยารักษาขั้นหายขาด

Abstract

Comparison study of anemia of 82 falciparum patients before and after received radical treatment, was done by measuring of their hematocrit values five times on day 0,14,28,42 and 56. Control groups consisted of 69 vivax patients and 944 non-malaria cases. The study found that, the anemia proportion of falciparum patient significant differed from vivax patients and non malaria cases. In additional, the anemia of falciparum patient was not depended on parasitemia levels. The rehabilitation of the anemia was depended on the duration after received radical treatment. Of falciparum patients, 48.07% of anemia patients, rehabililated on day 56 after had received radical treatment. The anemia of falciparum patients resisted to antimalarial drug was significant higher than the patients responded. From this study, the anemia of these patients was mostly chronic state, which could be anticipated that it depended on three factors, re-infections, malnutrition and antimalarial drug resistance.