Alpha-thalassemia 1 among Married Couples in Six Northeastern Provinces - แอลฟาธาลัสซีเมีย 1 ของคู่สมรสใน 6 จังหวัดในภาคอีสาน

Abstract

       The retrospective study of 1,368 cases of 684 couples from Ubon Ratchathani, Si Sa Ket, Amnat Charoen, Yasothon, Nakhon Phanom and Mukdahan provinces during June 2006 - May 2008 at clinical pathology section Regional Medical Science Center Ubon Ratchathani, was done to find out the status of alpha-thalassemia. The study reported the gestation periods of 3-40 weeks (x 14.6, SD 6.9), 13-46 years old (x 26.6, SD 6.8), proportions of positive OF and DCIP screening test among them were 94.9 and 61.0 percent, respectively. The husbands were 17-58 years old (x 30.2, SD 7.2), and proportions of positive OF and DCIP screening test were 94.6 and 47.4 percent There were a case of THAI (0.07%) and 139 cases of SEA type of alpha-thalassemia (10.16%).
Key words: alpha-thalassemia 1, northeastern provinces, married couples, clinical pathology