Efficacy and Safety of Periorbital Syringoma Treatment using Fractional Erbium YAG Laser

Abstract

Syringoma is a benign adnexal tumor of the skin, predominantly involving the periorbital areas which can cause significant cosmetic concerns for affected individuals. An ideal treatment of syringoma is selective destruction with little damage to the normal tissue which literally impossible for the conventional treatment modalities. The fractional erbium-doped yttrium aluminum garnet (erbium YAG) laser utilized in this study is unique that it has adjustable depth and coagulation parameters. The objective of this study was to demonstrate the efficacy and safety of fractional erbium YAG laser for treating periorbital syringomas. Ten patients with biopsy-proven periorbital syringomas were treated with 3 sessions of fractional erbium YAG laser at 6-week interval. Clinical evaluation performed at 1, 3 and 6 months after last treatment using photographic comparison revealed grade 4 clearance in 7 cases and grade 3 clearance in 3 cases. The clinical improvement scores at 1, 3 and 6 months after the last laser treatment were significantly different (p<0.05). Patient satisfaction was evaluated at 6 months post laser treatment with result of very satisfied in 4 cases and satisfied in 5 cases. No complications, such as scarring, erythema, and pigmentary changes, were observed. The authors concluded that the fractional Erbium YAG laser might be an alternative modality to treat periorbital syringoma to gain good cosmetic results without complications if applied repeatedly.