Serotype and Drug Resistance of Shigella Isolated from Patients in Trang Hospital during 2005-2006

Abstract

Shigella is the cause of shigellosis with manifestations of diarrhea with blood, fever and vomit, by many serotypes. Fifty-nine samples of Shigella isolated from patients in Trang hospital were sent to Regional Medical Sciences Center, Trang from 2005 to 2006 for confirmation and serotype identification by Edward Ewing method. Shigella sonnei phase I, II was reportedly the most predominant and found in thirty-one samples (52.54%), followed by Shigella sonnei phase II in twentyfour samples (40.64%), Shigella sonnei phase I in two samples (3.39%) and Shigella flexneri type 2a in two samples (3.39%). Drug susceptibilities of Shigella by the agar disk diffusion method with 8 antimicrobial agents such a ampicillin, tetracycline, co-trimoxazole, chloramphenical, streptomycin, norfloxacin, cefotaxime and ceftriaxone were investigated. Serogroup Shigella sonnei were most resistant to tetracycline and streptomycin (93.75%), co-trimoxazole (68.75%), ampicillin (43.75%), and chloramphenical (43.75%). All of Shigella isolated were susceptible to norfloxacin (100%), cefotaxime (100%) and ceftriaxone (100%).