Factors Associated with of Recurrent Benign Thyroid Nodule after Thyroidectomy : Prospective Study of 106 Patients-ความสัมพันธ์ระหว่างปัจจัยกับการเกิดเป็นซ้ำของก้อนทุมต่ำไทรอยด์ภายหลังจากที่ได้รับการรักษาโดยวิธีการผ่าตัด

Abstract

           Risk factors of developing recurrent thyroid nodules include young age and failure to use thyroid hormone replacement after surgery. However, evidence for thyroid hormone therapy was lacking in the literatures and its use was still controversial. This paper was aimed to study the relationship of age, gender, histology of the thyroid nodule and use of thyroid hormone post-operatively with the incidence of recurrent thyroid nodules. It is a prospective study of patients undergoing thyroid “lobectomy” or “hemi-thyroidectomy” between 1994 and 2006 for benign nodules. Patients with malignancy were excluded. Differences between factors and recurrence rates of the thyroid nodules were established by Fisher’s Exact test, independent t-test and odd ratio. Results showed recurrent nodules in 9 out of 106 cases or 8.49 percent. It was revealed that neither age, gender, histology type nor thyroid hormone use post-operatively affected recurrence rates of the thyroid nodules. Therefore, use of thyroid hormone after lobectomy or hemithyroidectomy for benign thyroid nodules is not only unnecessary but a waste of resources as portrayed in this long term follow-up study.

Key words: recurrence, thyroid nodule, risk factor, thyroid hormone