Predicting Factors of Dengue Shock Syndrome in Children

Abstract

A retrospective cohort study of pediatric patients with dengue hemorrhagic fever and dengue shock syndrome admitted at Chaoprayayommaraj Hospital between January 2010 and December 2011 was performed by collecting clinical and laboratory data from medical records. Predicting factors of dengue shock syndrome were analyzed by chi-square, t-test, simple and multiple logistic regression. Of the 207 patients, 167 were in a non-shock group and 40 were in a shock group. Independent predicting factors of dengue shock syndrome were percent of hemoconcentration from baseline and albumin level in early critical phase. The relative risks of shock were 4.1, 2.0 and 7.4 in patients with hemoconcentration more than 22 percent, albumin less than 3.5 g/dL. and both two criteria respectively. Bleeding other than petichiae, higher white blood cells count, higher AST and lower platelets count were correlated with dengue shock syndrome by chi-square, t-test and simple logistic regression but they were not independent predicting factors by multiple logistic regression. Sex, age and nutritional status were not associated with dengue shock syndrome