Intermittent Cyclical Bisphosphonates Therapy on Osteoporosis

Abstract

Osteoporosis is a major public health problem. Oral bisphosphonates are effective for reduction the risk of osteoporotic fracture and are an important treatment option for patients at risk for this condition. This prospective descriptive study included 18 osteoporotic patients. All patients received bisphosphonates continuously for 1 year. Then they received bisphosphonates intermittent cyclical therapy for 1 year. This result indicated that intermittent cyclical bisphosphonates could increase bone mass.