Prevalence of HPV Strains Form Cervical Cancer Screening by HPV DNA Test of 14 High Risk Strains in Health Regional 3, Thailand

Abstract

Cervical cancer is a major public health problem that is mainly caused by infection with high-risk HPV strains. It can develop into cervical cancer. Therefore, this study aimed to determine the prevalence of HPV strains. From cervical cancer screening using HPV DNA 14, high-risk strains, in Thai women aged 30-60 years, a total of 28,870 people received cervical cancer screening services in 2021 at the Regional Medical Science 3, Nakhon Sawan Province. From the study, the prevalence of HPV infection was found to be 7.69%, with the prevalence of strains 16, 18 and high-risk strains other than strains 16/18 being 1.19%, 0.48, and 6.02%, respectively. The highest prevalences were strains 52, 16, 58 and 68 at 1.35%, 1.19%, 0.63% and 0.63%, respectively. When evaluating cytological abnormalities thin sheets of high-risk strains other than strains 16/18 the abnormalities were at 20.07 percent, of which the top 5 were strains 33, 52, 58, 31, and 56 at 28.57, 23.14, 23.08, 22.95, and 21.11 percent, respectively. In addition, the positive predictive value of the cervical biopsy results was found to be 56.35%, 51.78%, and 43.80 respectively. The results of the study can be used as information for selecting the HPV vaccine to be appropriate for the population in the area.