Outcome of Treatment of Spinal Tuberculosis; Anti - tuberculosis Regimen VS Combined Treatment of Short- Course Two-Drug Therapy with Surgery - ผลของการรักษาวัณโรคกระดูกสันหลังด้วยยาต้านเชื้อวัณโรคกับการใช้ยาต้านเชื้อวัณโรคสองชนิดระยะสั้นร่วมกับการผ่าตัด : โรงพยาบาลราชบุรี

บทคัดย่อ

                       In a retrospective study, 50 cases of spinal tuberculosis were enrolled during January 2007 - December 2007, at orthopedics department Ratchaburi hospital.  Data were collected from medical records concerning gender, age, level of involved spines, medical modality and complications such as relapse, extension to thoracic spines and neural compression.  In data analysis, descriptive statistics were employed to describe general information and chi-square test, Fisher’s exact test to study associations between variables.  It was found that 33 cases (66%) were male aged 42.94 years.  Half of the cases (50%) were affected with TB of thoracic spine while the other half with TB of lumbar spine.  In that connection, 34 cases (68%) received anti-tuberculosis drugs, the rest 16 cases (32%) had Combined Treatment With Short-Course Two-Drug Therapy and surgery.  Complications, that followed, were 8 (16%) relapse cases, 11 cases (22%) of  extension to thoracic and 9 cases (18%) of neural compression.  Analysis for treatment complications of both groups showed no statistical significance at 0.05 level.

Key words:      spinal TB (Pottีs disease), relapse, thoracic vertebrae involved, neural compression