Follow-up of HIV Positive Women Who had Abnormal Pap Smear Screening Results at Sanpatong Hospital, Chiang Mai Province, Thailand - การติดตามสตรีติดเชื้อเอชไอวี ทีมีผลการตรวจคัดกรองมะเร็งปากมดลูกผิดปกติ โรงพยาบาลสันป่าตอง จังหวัดเชียงใหม่

บทคัดย่อ

HIV-reactive women have increased risk of squamous intraepithelial lesion; nevertheless cervical
cancer screening and treatment with effective follow up can reduce invasive risk. The objectives of
this study were to assess the outcomes of cervical cancer screening and follow-up the treatment outcome
among HIV-positive women attending Sampatong Hospital during January 2004 and December
2012. There were altogether 382 women with HIV who were screened with Pap smear during the study
period (with a total of 1,720 visits); and 107 of them had abnormal screening results: 18 with ASC,
2 with AGC, 53 with LSIL, 33 with HSIL, and 1 with suspicious cancer. Tissue diagnoses were
conducted, and the results revealed that 20 were normal, 43 were with LSIL, 39 with HSIL, and 5 with
invasive cancer. Follow up within 1-year revealed that there were 22 women (21.57%) with abnormal
screenings and the tissue diagnosis came out as 14 with LSIL, 6 with HSIL, and 2 had cervical cancer.
For those 90 women who were followed up to 1-year or more, 5 died, and 20 (23.53%) with
relapsed lesion (6 with LSIL and 14 with HSIL). Among 42 women with persisted lesions, 12 had had
normal colposcopic studies. The relapse after treatment implied that there was a need for annual cervical
cancer screening and continuous follow up for HIV-positive women.
Key words: HIV, long-term follow-up, Pap smear, recurrence cervical cancer