Incidence and Risk factors of Neonatal polycythemia in Takuapa hospital, Phang-nga province
Abstract
Background: Neonatal polycythemia is a common problem in newborns. By increasing blood viscosity, polycythemia can impair microcirculatory flow in end organs. The incidence of neonatal polycythemia in Takuapa hospital was increasing during the last five years.
Objectives: To determine the incidence and risk factors of neonatal polycythemia at Takuapa hospital.
Stydy design: A retrospective data were collected from medical records. The polycythemia neonates admitted to neonatal unit or NICU during the 1st January 2016 to the 31st August 2021 were included. Data collected including patient demography and risk factors related to neonatal polycythemia. Multivariate analysis and logistic regression were used to analyze the risk factors.
Results: The incidence of neonatal polycythemia during the 1st January 2016 to the 31st August 2021 was 0.40%, 0.60%, 1.99%, 2.15%, 0.96% and 2.69%. 85 polycythemia neonates were enrolled in the study with female 44.7% and male 55.3%. The mean venous hematocrit was 69.5%. The multiple logistic regression analysis showed a significant relationship between neonatal polycythemia and maternal gestational diabetes mellitus (OR 11.76; 95% CI 2.93,47.13), meconium stained amniotic fluid (OR 14.99; 95% CI 1.44, 155.62), low birth weight (<2,500 grams) (OR 6.69; 95% CI 2.53, 17.65) and large for gestational age (≥4,000 grams) (OR 8.31; 95% CI 2.61, 26.46).
Conclusions: The incidence of neonatal polycythemia in Takuapa hospital was increasing during the 1st January 2016 to the 31st August 2021. The risk factors strongly associated with neonatal polycythemia were meconium stained amniotic fluid, maternal gestational diabetes mellitus, low birth weight (<2,500 grams) and large for gestational age (≥4,000 grams).
Keywords: Neonatal polycythemia, Incidence, Risk factors
