The Effect of BMI with Respiratory Comorbidities on Prolonged Mechanical Ventilation (PMV) in Critically Ill Patients in Phrae Hospital
Keywords:
prolonged mechanical ventilation, BMI, respiratory comorbiditiesAbstract
Background: PMV is a cause of high mortality rate in the critically ill patients at Phrae hospital. One of the most important risks is high body mass index (BMI), and respiratory diseases, but also no previous research study the relationship between BMI and PMV use with respiratory comorbidities.
Objective: To study the effect of having respiratory comorbidities on the relationship between BMI and PMV uses in critically ill patients at medical intensive care unit (MICU), Phrae hospital.
Study design: A retrospective cohort study, including the patients first used mechanical ventilator at MICU from January 1, 2019 to October 31, 2022. The exclusion criteria were the patients who died within 21 days, and had not recorded BMI within one month before use. The population was 176 and grouped by BMI criteria into three groups. Multivariable logistic regression was used for analyzing the data, showing odds ratio with 95% CI.
Results: The regression coefficient (β) value of being PMV is 0.15 (95% CI: -2.63 to 3.55), and 0.96 (95% CI: -1.61 to 4.25) from patients with low BMI and having respiratory comorbidities, and high BMI and having respiratory comorbidities, respectively. The odds of having PMV is 1.12 times (95% CI: 0.40-2.97) from low BMI patients and 1.80 times (95% CI: 0.78-4.25) from high BMI after adjusting confounders.
Conclusion: We cannot conclude that respiratory comorbidities affect on PMV both low and high BMI; However, high BMI patients are prone to have PMV. This finding could be used to closely monitor them, and early make tracheostomy decisions to reduce complications from PMV.
Keywords: prolonged mechanical ventilation, BMI, respiratory comorbidities
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