Develop and Usable a Warfarin Mobile App with no-Code and Free: New Case Drug Management

Authors

  • Worawit Thungwilai Sawanpracharak Hospital
  • Perayot Pamonsinlapatham Silpakorn University Nakhon Pathom

Keywords:

Warfarin, Mobile Application, No-Code, Thunkable, Medication Adherence

Abstract

Objectives: 1. To develop a medication tracking and patient care system through a no-code mobile application. 2. To promote medication adherence among patients. 3. To assess patient satisfaction with the mobile application.

Methods: This study was conducted among new warfarin users in the internal medicine and stroke wards at Sawanpracharak Hospital between July and August 2023. Patients were divided into two groups, each comprising 30 participants. The control group received standard medication counseling from pharmacists, while the experimental group received the same counseling plus medication tracking via the mobile application. Follow-up was conducted twice, to evaluate INR values, medication adherence, and application satisfaction.

Results: In the control group, the percentage of patients with INR values within the target range at the two follow-ups was 26.67% and 33.33%, respectively. In the experimental group, it was 90.00% and 96.67%, respectively. No severe adverse events were reported in either group. The experimental group had a lower INR variance than the control group (0.08 vs. 2.69, respectively). Chi-square testing showed that patients in the experimental group were significantly more likely to have INR values within the target range than those in the control group (p-value<0.05). Application satisfaction was rated as good, with scores exceeding 4.0 out of 5.0 across all categories. The findings suggest that mobile applications improved medication adherence and helped patients achieve target INR values from the first follow-up.

Conclusion: The no-code mobile application developed in this study effectively tracked warfarin use and represents a new option for individuals without a technology background who wish to create practical tools.

Keywords: Warfarin, Mobile Application, No-Code, Thunkable, Medication Adherence

References

Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093–100.

January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS Focused Update of the 2014 Guideline for the Management of Patients With Atrial Fibrillation. J Am Coll Cardiol. 2019;74(1):104–32.

Heneghan CJ, Garcia-Alamino JM, Spencer EA, Ward AM, Perera R, Bankhead C, et al. Self-monitoring and self-management of oral anticoagulation. Cochrane Database Syst Rev. 2016;(7): CD003839.

Lam WY, Fresco P. Medication adherence measures: an overview. Biomed Res Int. 2015;2015:217047. Doi:10.1155/2015/217047

Kini V, Ho PM. Interventions to improve medication adherence: a review. JAMA. 2018 Dec 18;320(23):2461–73. Doi:10.1001/jama.2018.19271.

Shrestha S, Althubaiti G, Shrestha S, Bhandari R, Poudel RS. Use of mobile health applications for chronic disease management, medication adherence, and patient education: a systematic review. Healthcare (Basel). 2023;11(5):711. Doi:10.3390/healthcare11050711

Saffian SM, Braithwaite I, Harding SA, Kerr AJ. Mobile health interventions for improving adherence in cardiovascular patients: a systematic review. Heart Lung Circ. 2021;30(12):1827-1840. Doi:10.1016/j.hlc.2021.06.522

Lee JA, Nguyen AL, Berg J, Amin A, Bachman M, Guo Y, Evangelista L. Attitudes and preferences on the use of mobile health technology and health games for self-management: interviews with older adults on anticoagulation therapy. JMIR Mhealth Uhealth. 2014;2(3):e32. Doi:10.2196/mhealth.3196

Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Atun R, Car J. Mobile phone messaging reminders for attendance at healthcare appointments. Cochrane Database Syst Rev. 2013;(12): CD007458. Doi:10.1002/14651858.CD007458.pub3

Labovitz DL, Shafner L, Reyes Gil M, Virmani D, Hanina A. Using artificial intelligence to reduce the risk of nonadherence in patients on anticoagulation therapy. Stroke. 2017;48(5):1416-1419. Doi:10.1161/STROKEAHA.116.016281

Sunderji R, Gin K, Shalansky K, Chambers K, Poulin C, Treharne C, et al. Clinical impact of point-of-care vs laboratory measurement of anticoagulation. Am J Clin Pathol. 2013;140(3):359-364. Doi:10.1309/AJCPGAL3FLLHWLOH

Merone M, Haas JP, Rizzo G, Skiada C, Scamarcia A, Seixas A, et al. Mobile apps in cardiology: review. JMIR Mhealth Uhealth. 2021;9(5):e19302. Doi:10.2196/19302

The Heart Association of Thailand. Guidelines for the treatment of patients on oral anticoagulants. National Health Security Office (NHSO); 2011.

Published

2025-06-23

How to Cite

Thungwilai, Worawit, and Perayot Pamonsinlapatham. 2025. “Develop and Usable a Warfarin Mobile App With No-Code and Free: New Case Drug Management”. Region 3 Medical and Public Health Journal - วารสารวิชาการแพทย์และสาธารณสุข เขตสุขภาพที่ 3 22 (2). Nakhonsawan Thailand:162-69. https://thaidj.org/index.php/smj/article/view/16504.

Issue

Section

นิพนธ์ต้นฉบับ (Original Article)