Thymoma in an adult woman with myasthenia gravis : a case report
Keywords:
Thymoma, anterior mediastinal mass, myasthenia gravisAbstract
A case of a 37-year-old woman who presented with chronic cough, dyspnea, and weight loss for 3 months. On chest radiograph, revealed an anterior mediastinal mass. Further chest computed tomography (CT) showed the large homogenous enhanced anterior mediastinal mass. The percutaneous needle biopsy was performed, the preliminary diagnosis is diffuse large B cell lymphoma. She developed clinically myasthenia gravis after 2nd cycle chemotherapy. Finally, the pathological diagnosis was thymoma.
Thymoma is the most common anterior mediastinal mass. The peak incidence is between ages 40 to 60 years, however, the gender distribution is approximately equal.
Thymomas are associated with a variety of paraneoplastic syndrome especially myasthenia gravis, that coexist or after post thymectomy. Prognosis depends on age and histological subtype. The histological subtype A, AB and B1 or patient with myasthenia gravis show good prognosis.
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