Factors related to amputation of diabetic foot in Nongbuadaeng hospital, Chaiyaphum Province
Keywords:
Amputation, Diabetic foot ulcer, Diabetes mellitus, Risk factorsAbstract
Purpose: To assess the risk factors of amputation in patients with diabetic foot ulcers (DFU)
Materials and Methods: The retrospective study was conducted on 177 patients with DFUs from October 2015 to September 2019. Their demographic characteristics, disease history, laboratory data, foot deformities, Wagner classification, osteomyelitis and ulcer sizes were considered as variables to predict outcome. A chi-square test and multivariate logistic regression analysis were performed to test the relationship of the data gathered. Additionally, the subjects were divided into two groups based on their amputation surgery.
Results: Among the 177 subjects, the amputation group, 106 subjects. The mean age of the subjects and the mean body mass index were 61 years; no significant difference. Duration of diabetes (Odd ratio[OR], 2.917; 95% confidence interval [CI],1.483-5.747) Osteomyelitis (OR, 2.473; 95%CI, 1.034-6.381) Hypertension (OR, 3.149; 95%CI, 1.398-7.221) Wagner’s Classification ≥ grade 4 (OR, 7.000; 95%CI, 0.875-315.338) Serum Albumin<3 g/dl (OR, 2.971; 95%CI, 1.153-8.595) estimated glomerular filtration rate (eGFR ;OR, 2.011; 95%CI, 1.044-3.877) and HbA1c>9% (OR, 2.008; 95%CI, 1.026-3.929) were associated with risk of amputation.
Discussion and Conclusions: The predictive factors for LEA in diabetic foot for this study were statistically significant from this study. Further investigation would contribute to the establishment of a diabetic foot risk stratification system, allowing for optimal individualized treatment. The multidisciplinary team with effective treatment in these patients; help to reduce the complications and loss of organs in the future as well.
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