Development of Alcohol Hand Cleansing Gel Formulas - การพัฒนาสูตรแอลกอฮอล์เจลสำหรับล้างมือ

Abstract

        Using alcohol gel for hand-rubbing is more convenient than washing with soap and water and is important factor for prevent cross infections among clients or patients leading to effective nosocomial infection control in the hospital. Previously high cost alcohol gel had to be purchased annually. The main objective of this experimental study develop was to evaluate five different formulas of alcohol hand cleansing gel. The stability of preparations was tested by freeze thaw cycle and the physical property in 50 volunteers. It was found that the most satisfying alcohol gel was the fifth formula with average score 4.66, 0.66 or 93.20 percent whereas the fourth and the third formula had
average scores of 4.44, 0.76 and 4.14, 0.83 respectively. The fifth formula was made up of carbopol 940 0.2% as a gelling agent, glycerine 1% and propylene glycol 2% as a humectant, triethanolamine 0.1%t as an acid-base balance for increasing viscosity and alcohol 70% as an antiseptic. This formula shows good stability, appropriate viscosity, is a good moisturizer and satisfying. The costbenefit ratio shows that it can save cost.
Key words: alcohol gel, develop formula