Efficacy of throat washing for follow up confirmed COVID-19 patients and Case series of confirmed COVID-19 patients in Sawanpracharak hospital
Keywords:
COVID-19, throat washing, nasopharyngeal/throat swabAbstract
Objective : To study efficacy of throat washing in detection SARS-CoV-2 after completion of treatment of confirmed COVID-19 patients, which collected by themselves compared with nasopharyngeal/throat swab, which collected by healthcare personnel and to report case series of confirmed COVID-19 cases in the first outbreak in Sawanpracharak hospital.
Method : This study is retrospective cohort study and case series report which studied in isolation cohort ward, Sawanpracharak hospital. Confirmed COVID-19 patients who were admitted in Sawanpracharak hospital between March 2020 – May 2020. Total subjects were seven patients were studied. Confirmed COVID-19 patients were completely treated and their signs and symptoms were resolved. Patients were instructed to collect throat washing fluid by themselves and were nasopharyngeal/throat swabbed by healthcare personnel every three days until specimens showed negative results for SARS-CoV-2. Then patients were discharged from hospital. Data was analyzed by descriptive, analytic statistics to calculate validity, predictive value and efficacy.
Results : A total of seven confirmed COVID-19 patients were admitted in isolation cohort ward, Sawanpracharak hospital. Median age was 43 years old (range 22-54 yrs). None of these patients had severe disease, respiratory failure and expired. Median of hospitalization were 22 days (range15-35days). Six patients were tested for detection SAR-CoV-2 after complete treatment. Throat washing has sensitivity 41.67%, specificity 66.67%, positive predictive value 71.43%, negative predictive value 33.36%, efficacy 50% compared with nasopharyngeal/throat swab.
Conclusions : Self collected throat washing had specimens low efficacy to detect SARS-CoV2 compared with nasopharyngeal/throat swab which collected by healthcare personnel in setting of posttreatment confirmed COVID-19 patients. Throat washing could not replace nasopharyngeal/ throat swab in this setting. However, limitation of this study was low number of patients, thus more studies should be done in next outbreak of COVID-19 in order to include more information from the patients.
Keywords : COVID-19, throat washing, nasopharyngeal/throat swab
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