ประสิทธิภาพของการตรวจหาเชื้อเฮลิโคแบคเตอร์ ไพโลไร ด้วยวิธีการตรวจอุจจาระในผู้ป่วยที่มาอาการทางเดินอาหารส่วนต้น

Papatsakorn Nopjaroonsri

Authors

Papatsakorn Nopjaroonsri Gastroenterology, Department of Medicine, Sawanpracharak Hospital

Keywords:

Helicobacter pylori, Stool antigen test, Stool Helicobacter pylori antigen

Abstract

Background: Helicobacter pylori infection is usually acquired in early childhood. Helicobacter pylori infection can cause gastritis, peptic ulceration, gastric adenocarcinoma, and some types of gastric lymphoma. Most diagnostic tests are based on invasive tissue biopsies, such as tissue culture, histology, or rapid urease test. There are also alternative noninvasive tests, such as urea breath testing, serological test, and stool antigen test

Objective: This study aimed to compare the diagnostic properties of the noninvasive stool antigen test with the invasive rapid urease test of patients who complain of upper gastrointestinal symptoms.

Methodology: A total of 82 dyspeptic patients from May 2022 to September 2022 who had not previously been treated for Helicobacter pylori infection were prospectively enrolled. After endoscopy and gastric tissue biopsy, the stool specimens were taken. The results of the rapid urease test were compared to the results of the stool antigen test in all patients.

Results: In this study, 34 of the 82 patients (41.5%) were positive results from the rapid urease test, and 48 patients (58.5%) were negative results. In comparison, 32 patients (39.0%) had positive results from the stool antigen test, and 50 (61.0%) were negative. The two test results were relatively comparable.

Conclusion: The stool antigen test is an easy, noninvasive, and inexpensive method for detecting Helicobacter pylori infection. The stool antigen test could be an alternative to invasive Helicobacter pylori infection tests.

Keywords: Helicobacter pylori; Stool antigen test; Stool Helicobacter pylori antigen

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