ลักษณะทางคลินิกและปัจจัยเสี่ยงของการเสียชีวิตของผู้ป่วยในหอผู้ป่วยวิกฤตโควิด-19 โรงพยาบาลสวรรค์ประชารักษ์

Porames Khunrong

Authors

Porames Khunrong Department of Medicine, Sawanpracharak Hospital

Keywords:

COVID-19, Patient Characteristics, Mortality

Abstract

Objective : This study aimed to study clinical characteristics and factors that affect patients mortality in COVID-19 intensive care unit

Method : Retrospective cross-sectional study of patients admitted to the COVID-19 intensive care unit From September 1, 2021 to June 30, 2022. A total of 359 people were collected from medical records in a computer system consisting of basic information, clinical symptoms, the severity of COVID-19, comorbidities, vital signs, laboratory tests, treatment information, complications, and vaccination history. Clinical characteristics and factors that affect mortality were analyzed using Inferential statistics: Chi-square test or Fisher’s exact test, t-test, and multivariable logistic regression with a 95% confidence interval (CI).

Results : Multivariable logistic regression data analysis showed that factors that significantly affected mortality included the use of vasopressors (Adjusted Odd ratios (ORadj) = 8.85; 95% CI: 3.98-9.71), endotracheal intubation (ORadj = 7.93; 95% CI: 3.89-16.15), COPD as comorbidity (ORadj = 5.07; 95% CI: 1.66-15.51), the using of methylprednisolone (ORadj = 4.78; 95% CI: 1.09-21.05), pre-hospital diarrhea (ORadj = 4.38; 95% CI: 1.20-16.00), acute kidney injury (Oradj = 3.63; 95% CI: 1.78-7.03), and over 65 years old (ORadj = 0.42; 95% CI: 0.21-0.85).

Conclusion : Factors that affect mortality in COVID-19 patients included using vasopressors, endotracheal intubation, COPD, the use of methylprednisolone, pre-hospital diarrhea, acute kidney injury as a complication, and being over 65 years old.

Key words : COVID-19, Patient Characteristics, Mortality

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