การศึกษาความสัมพันธ์ของความรู้ทัศนคติต่อความร่วมมือในการกินยาของผู้ป่วยโรคซึมเศร้า: การศึกษาภาคตัดขวางในโรงพยาบาลสงขลา

Laddaporn  Tepsuan

Authors

Laddaporn Tepsuan Songkhla Hospital

Keywords:

Knowledge, attitudes, depression, antidepressant adherence

Abstract

Objective: This study aims to assess the level of knowledge and attitudes towards depression, as well as medication adherence among patients, and to investigate the relationship between knowledge, attitudes, and medication adherence in patients with depression at Songkhla Hospital.

Methods: A cross-sectional study was conducted with a sample of 382 patients diagnosed with depression who were receiving treatment at the Psychiatry Clinic, Songkhla Hospital. Data collection tools included a personal information questionnaire, a knowledge and attitude questionnaire toward depression, a Medication Adherence Scale (MAST), the Patient Health Questionnaire-9 (PHQ-9), and additional questionnaires regarding stigma and the doctor-patient relationship. Data were analyzed using Epi-Data software with descriptive statistics and multiple logistic regression and Mann–Whitney U test to examine relationships between variables.

Results: A total of 382 patients participated in the study, with an average age of 39 years (range 25–52 years), 83.5% of whom were female and 16% were male. Analysis revealed that factors significantly related to depression included age (p-value<0.001), occupation (p-value=0.008), family relationship perception (p-value<0.001), and stigma (p-value=0.003). Unemployed individuals were 5.93 times more likely to experience depression compared to students (95% CI=1.90, 18.51), and those with poor family relationships were 6.92 times more likely to have depression compared to those with good family relationships (95% CI=2.89, 16.58). The study also showed that patients with positive knowledge and attitudes towards depression were more likely to adhere to their medication, though no statistically significant relationship was found (p-value=0.183 and 0.590, respectively). Additionally, 95.5% of patients were consistent in taking their medication, and 80.6% had a good relationship with their doctor.

Conclusion: The study found that knowledge and attitudes towards depression were associated with self-care and medication adherence, but no statistically significant relationship was found with depression severity and treatment cooperation. Patients with positive knowledge and attitudes towards depression tended to be more consistent in taking their medication and emphasized self-care. However, statistically significant factors associated with depression included age, occupation, family relationship perception, and stigma, with unemployed individuals and those with poor family relationships being at higher risk for depression.

Keywords: Knowledge, attitudes, depression, antidepressant adherence

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