Comparing the Effectiveness of Tubal Sterilization Performed Under Intravenous Anesthesia Using Ketamine and Midazolam, with and without Local Infiltration of Lidocaine at Kalasin Hospital in 2024
Keywords:
lidocaine infiltration, postoperative pain, tubal ligation, rescue analgesiaAbstract
Introduction: lidocaine skin infiltrating aimed at reducing peri- and post-operative pain also minimizing anesthetic drugs and opioid consumption. This study investigates the effectiveness of lidocaine skin infiltration in conjunction with intravenous ketamine and midazolam during female tubal ligation.
Methods: a prospective randomized controlled trial was conducted involving 60 female who were randomly assigned to receive either 2% lidocaine with adrenaline infiltration and normal saline (as a control group) before surgery. All participants received intravenous midazolam and ketamine. Post-surgery pain scores were assessed, along with additional analgesia and side effects. Compared characteristics and treatment results by Chi square test or Fisher’s exact test and student T test or Wilcoxon Rank Sum Test
Results: The study group had a significantly lower proportion of receiving Rescue-Ketamine-Dose (RKD) (3.3% vs. 80.0%) (p-value < 0.01) and significantly lower postoperative pain scores compared to the control group. The study group also had a lower median additional ketamine dose (0.5 vs. 0.5 mg/kg) (p-value < 0.01) and a significantly lower proportion of fentanyl administration (16.7% vs. 86.7%) (p-value < 0.01) than the control group
Conclusion: lidocaine skin infiltration reduces proportion of requiring RKD as well as reduces post-tubal ligation pain and decreases the need for additional analgesics, enhancing patient comfort while minimizing using pain control.
Keywords: lidocaine infiltration, postoperative pain, tubal ligation, rescue analgesia
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