Epidemiology of Acute Urticaria in Children at a Community Hospital

Authors

  • Natnicha Praphaphanthasak Pediatrician, Professional Level, Pediatrics Department, Khumuang Hospital Buriram Province

Keywords:

acute urticaria, pediatric urticaria, incidence, triggering factors, community hospital

Abstract

          Acute urticaria is a common skin condition in children and a frequent reason for seeking medical care. This study aimed to determine the incidence, temporal patterns, clinical characteristics, suspected triggers, and factors associated with hospitalization among children with acute urticaria. This retrospective analytical cross-sectional study reviewed electronic medical records of children aged 28 days to 15 years diagnosed with acute urticaria at Khu Mueang Hospital, Buriram Province, Thailand, from January 1, 2023, to December 31, 2025. Descriptive statistics were used, incidence rates with 95% confidence intervals (CIs) were calculated, temporal patterns were analyzed using Poisson regression, and factors associated with hospitalization were assessed using univariable logistic regression.

          A total of 360 patients were included. The average annual incidence was 13.90 per 1,000 children (95% CI 12.47–15.33). A significant seasonal pattern was observed (p < 0.001), with incidence peaking from late July to August and being approximately 2.65 times higher than at its lowest point. Children aged 1–5 years constituted the largest age group (35.0%). Most cases had idiopathic (66.9%), followed by infection (10.3%) and physical factors (8.3%). Overall, 5.0% were hospitalized. Fever (OR 6.97, 95% CI 2.63–18.49; p < 0.001) and infection as a suspected trigger (OR 5.02, 95% CI 1.76–14.29; p = 0.003) were associated with hospitalization.

          Acute pediatric urticaria showed stable incidence over three years but a distinct seasonal pattern, peaking from late July to August. Most cases had no identifiable trigger, while fever and suspected infection were associated with hospitalization. These findings may support pediatric healthcare planning and provide baseline epidemiological data for community hospital settings.

References

Zuberbier T, Abdul Latiff AH, Abuzakouk M, Aquilina S, Asero R, Baker D, et al. The international EAACI/GA²LEN/ EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy 2022;77(3):734-66. DOI:10.1111/all.15090.

Antia C, Baquerizo K, Korman A, Bernstein JA, Alikhan A. Urticaria: a comprehensive review: epidemiology, diagnosis, and work-up. J Am Acad Dermatol 2018;79(4):599-614. DOI:10.1016/j.jaad.2018.01.020

Kolkhir P, Giménez-Arnau AM, Kulthanan K, Peter J, Metz M, Maurer M. Urticaria. Nat Rev Dis Primers 2022;8(1):61. DOI:10.1038/s41572-022-00389-z

Koumaki D, Koumaki V, Boumpoucheropoulos S, Katoulis A, Laguda B. Childhood acute urticaria and seasonal patterns presenting in the emergency department of a teaching hospital in London, United Kingdom. Pediatr Emerg Care 2022;38(1):e385-6. DOI:10.1097/PEC.0000000000002297

Techasatian L, Phungoen P, Chaiyarit J, Uppala R. Etiological and predictive factors of pediatric urticaria in an emergency context. BMC Pediatr 2021;21(1):92. DOI:10.1186/s12887-021-02553-y

Delice O, Güçlü Utlu S, Arslan Ş, Doru HI, Daş M. The impact of meteorological parameters on the number of applications to the emergency department with acute urticaria: a retrospective study. PLoS One 2023;18(9):e0290535. DOI:10.1371/ journal.pone.0290535

Coelho I, Neto B, Bordalo D, Jacob S. Urticaria in a pediatric population: a Portuguese single-center cohort report. Cureus 2022;14(7):e26659. DOI:10.7759/cureus.26659

Kim EJ, Zhang Z, Hlobik M, Ho T, Huang JT. Urticaria in infants: a single-institution retrospective study. Pediatr Dermatol 2024;41(2):260-2. DOI:10.1111/pde.15519

Caffarelli C, Paravati F, El Hachem M, Duse M, Bergamini M, Simeone G, et al. Urticaria in childhood. Acta Biomed 2020;91(11-S):e2020013. DOI:10.23750/abm.v91i11-S.1031

Talarico V, Marseglia GL, Lanari M, Esposito S, Masi S, De Filippo M, et al. Pediatric urticaria in the emergency department: epidemiological characteristics and predictive factors for its persistence in children. Eur Ann Allergy Clin Immunol 2021;53(2):80-5. DOI:10.23822/ EurAnnACI.1764-1489.148

Sekerel BE, Ilgun Gurel D, Sahiner UM, Soyer O, Kocaturk E. The many faces of pediatric urticaria. Front Allergy 2023;4:1267663. DOI:10.3389/falgy.2023.1267663

Peck G, Hashim MJ, Shaughnessy C, Muddasani S, Elsayed NA, Fleischer AB Jr. Global epidemiology of urticaria: increasing burden among children, females and low-income regions. Acta Derm Venereol 2021;101(4):adv00433. DOI:10.2340/00015555-3796

Ansotegui IJ, Bernstein JA, Canonica GW, Gonzalez-Diaz SN, Martin BL, Morais-Almeida M, et al. Insights into urticaria in pediatric and adult populations and its management with fexofenadine hydrochloride. Allergy Asthma Clin Immunol 2022;18(1):41. DOI:10.1186/s13223-022-00677-z

Liu S, Jing X, Feng F, Wang H, He T. Global burden of urticaria in children and adolescents, 1990 to 2021: trends, disparities, and future projections. Medicine (Baltimore) 2026;105(5):e47488. DOI:10.1097/MD.0000000000047488

da Costa Farinha IF, Pereira H, de Lemos SCG, de Faria E, Rodrigues FMP. Hospital admissions for urticaria in a pediatric emergency department of a tertiary care hospital. Allergol Immunopathol (Madr) 2023;51(3):117-23. DOI:10.15586/aei.v51i3.820

Bezirganoglu H, Arik Yilmaz E, Sahiner UM, Soyer O, Sekerel BE, Teksam O, et al. The common triggers of urticaria in children admitted to the pediatric emergency room. Pediatr Dermatol 2022;39(5):695-701. DOI:10.1111/pde.15020

Zaryczanski J, Ochab A, Ochab M, Zaryczanska A, Brzoza Z, Chobot A. D-dimer concentrations in acute urticaria in children. Allergol Immunopathol (Madr) 2021;49(1):107-12. DOI:10.15586/aei.v49i1.30

Shin M, Lee S. Prevalence and causes of childhood urticaria. Allergy Asthma Immunol Res 2017;9(3):189-90. DOI:10.4168/aair.2017.9.3.189

Pité H, Morais-Almeida M. A practical up-to-date approach to managing acute urticaria in children. Curr Treat Options Allergy 2024;11(3):176-83. DOI:10.1007/s40521-024-00370-z

Colak O, Guleryuz OD, Men Atmaca Y, Senkalfa B, Akca Caglar A, Tomar GS. A retrospective study to describe the clinical pattern of dermatologic lesions from the pediatric emergency department: our experience from a tertiary care hospital in Turkey. Postgrad Med 2023;135(6):601-6. DOI:10.1080/00325481.2023.2225301

Suntronwong N, Vichaiwattana P, Puenpa J, Pasittungkul S, Aeemjinda R, Wongsrisang L, et al. Seasonal pattern and age-specific detection of eight respiratory viruses causing acute respiratory infection in 2024, Bangkok, Thailand. Trop Med Infect Dis 2025;10(12):339. DOI:10.3390/tropicalmed10120339

Ugwu N, Cheraghlou S, Antaya RJ, Feng H, Cohen JM. Trends in office visits and treatment for urticaria in children in the United States, 1998-2016. Pediatr Dermatol 2021;38(5):1162-8. DOI:10.1111/pde.14726

Yigit RE, Cavkaytar O, Besli GE, Arga M. Do pediatric emergency physicians comply with guideline recommendations in management of patients with acute urticaria?. Pediatr Emerg Care 2021;37(8):407-12. DOI:10.1097/PEC.0000000000002327

Brehler ACE, Bauer A, Wedi B. Urticaria in childhood—what's new?. Allergo J Int 2023;32:318-25. DOI:10.1007/s40629-023-00271-8

Published

2026-08-20

Issue

Section

Original Article