Risk factors for morbidity and mortality of operated perforated peptic ulcer patients in Loei hospital
Keywords:
patient with peptic ulcer perforation, risk factor of postoperative, morbidity and mortalityAbstract
Perforated peptic ulcer is a common complication of peptic ulcer disease. The morbidity and mortality still high. Surgical management is essential in almost patients. Optimal surgical management and proper perioperative care may reduce the morbidity and mortality of these patients.
Objective: To find out the risk factors for morbidity and mortality of operated perforated peptic ulcer patients.
Material and method: Retrospective study of 302 patients who operated for perforated peptic ulcer at Loei Hospital from 2016 to 2019. The patients characteristic, type of ulcer, time from perforation to operation, type of operation, result of treatment, and complication were analyzed .
Result: 302 patients were included in this study. 267 patients were male (88%) and 35 patients were female (12%). The mean age ± 14years (range 17-95 years). 12 patients were die (4%) and 29 patients have post-operative complication (10%). On multivariable logistic regression analysis show that associated medical illness and time from perforation to operation more than 24 hours (perforation-operation time interval) were significantly associated with high morbidity and mortality of operated perforated peptic ulcer patients.
Conclusion: Perforated peptic ulcer patients still have high morbidity and mortality. Early diagnosis, adequate resuscitation, and timely operation may improve outcome of patients especially in high risk patients.
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