Risk Factors of Carbapenem-Resistant Bacteria Infection in Stroke Patients at Sakon Nakhon Hospital : ปัจจัยเสี่ยงต่อการติดเชื้อแบคทีเรียดื้อยาคาร์บาพีเนม ในผู้ป่วยโรคหลอดเลือดสมอง โรงพยาบาลสกลนคร

Authors

  • Anuwat Surinrach
  • Anusak Kerdsinp
  • Praputsorn Somsri

Abstract

          This unmatched case-control study aimed to determine the risk factors associated with carbapenem-resistant Enterobacteriaceae (CRE) and/or carbapenem-resistant Acinetobacter baumannii (CRAB) in stroke patients admitted in stroke unit of Sakon Nakhon hospital. The case group was stroke patients infected with CRE and/or CRAB while the control group was stroke patients without CRE and/or CRAB infection, 60 patients in each group. The data were collected from the patient records and database of microbiology laboratory, Sakon Nakhon hospital from April 1st, 2016 to December 31st, 2018. Baseline data were analyzed using descriptive statistics. The inferential statistics, logistic regression, were applied to analyse the association between the independent variables and the CRE and/or CRAB infection. A p-value of 0.05 was considered significance.

          The results revealed that in the case group, 28 patients were CRE infection (46.70%) and 32 patients were CRAB infection (53.30%). The CRE and/or CRAB infections were mostly caused by ventilator-associated pneumonia (76.60%); followed by catheter-related urinary tract infection (20%). The risk factors of CRE and/or CRAB infection in patients were the previous antibiotic uses (ORadj= 3.3; 95%CI = 1.2-9.1), the hospitalization more than twenty days (ORadj= 2.6; 95%CI = 1.1-6.2), endotracheal tubes insertion (ORadj= 9.8; 95%CI = 1.3-75.5) and nasogastric tube intubation (ORadj= 9.3; 95%CI = 1.2-74.5). Thus the stroke patients with those risk factors should be provided intensive nursing guidelines and care to prevent and control CRE and/or CRAB infection.

          Keywords : stroke patients, CRE, CRAB, risk factors

Published

2019-08-29

Issue

Section

Original Article