Prevalence and Risk Factors for Recurrent Febrile Seizures after First Episode of Febrile Seizure in Pediatric Patients at Sawanpracharak Hospital
Keywords:
Febrile seizure, Prevalence, Risk factors, PediatricAbstract
Objective : To study prevalence and risk factors for recurrent febrile seizures (FS) after having the first seizure in pediatric patients at Sawanpracharak Hospital.
Method : This study was a retrospective cohort study in pediatric patients, aged from 6 months to 5 years old, who were diagnosed with initial FS at Sawanpracharak Hospital between January 2015 to December 2017. 255 patient medical records in the databases were revised. Statistics used to estimate was the rate of recurrent FSs with the binomial distribution theory. The recurrence rate was reported in percentage and 95% CI. The logistic regression was used to find risk factors for recurrent FSs and the level of statistical significance was determined at p-value < 0.05.
Results : The median age of pediatric patients with FSs was 18.1 (IQR 11.2-27.6) months, mainly males 58.8%. Fifty-eight of them (22.7%) had recurrent FSs after an initial seizure. The age of patients with the first seizure of less than 24 months (OR, 2.47; 95%CI, 1.11-5.51; p=0.03) and the complex type of first seizure (OR, 2.28; 95% CI, 1.12-4.64; p=0.02) were statistically significant risk factors for recurrent FSs after the first seizure. Acute pharyngitis was the most common cause of the first and second seizures. Gender, body temperature during the first seizure, duration of fever prior to an initial seizure, family history of FSs and epilepsy were not risk factors for recurrent FSs.
Conclusion : Apart from monitoring, knowledge and advice should be given to parents of seizure patients, especially in groups at risk of recurrent febrile seizures, so parents can provide proper care, lead to reduce concerns and various complications that may occur in children.
Keywords : Febrile seizure, Prevalence, Risk factors, Pediatric
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