Persistent Pulmonary Hypertension of the Newborn at Somdejphrajaotaksinmaharaj Hospital
Keywords:
Infants, Persistent pulmonary hypertension of the newborn, Mortality rateAbstract
Objective : The objective is to determine the incidence, clinical description, treatment, outcome and mortality rates of infants with persistent pulmonary hypertension of the newborn (PPHN)
Method : This research is a retrospective descriptive study. Medical records of infants who were diagnosed PPHN at Somdejphrajaotaksinmaharaj hospital between 1st January 2017 to 31st July 2021.
Results : 29 infants were diagnosed with PPHN during this period. The incidence of PPHN was 3.7 per 1,000 live births. 8 of 29 diagnosed PPHN newborns were males (27.6%). Thai nationality 93.1%. Mean gestational age was 32.7 ± 5.1 weeks. There was 65.5% delivered by normal labour. Most common causes of PPHN were respiratory distress syndrome (RDS) and birth asphyxia (62.1%). The mortality rate of PPHN was 75.9%. The non-survivor group had gestational age and birth weight lower than the survivor group with statistically significant (p-value =0.008). The non-survivor group was diagnosed RDS more than the survivor group with statistically significant (p-value=0.03).
Conclusions : The mortality rate of PPHN at Somdejphrajaotaksinmaharaj hospital remained high. The majority cause were RDS and birth asphyxia. The risk factors related to mortality in PPHN were low gestational age, low birth weight and RDS
Keywords : Infants, Persistent pulmonary hypertension of the newborn, Mortality rate
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