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Prevalence and predictive factor for bacteremia in children with urinary tract infection at Sawanpracharak hospital

Authors

  • Nutnari Poopattanagul Sawanpracharak Hospital

Keywords:

Urinary tract infection, Bacteremia, Risk factors, Pediatrics

Abstract

Objective      : To study prevalence and risk factors for bacteremia in pediatrics with urinary tract infection at Sawanpracharak Hospital.

Method       : This study was a retrospective cohort study in pediatrics with aged less than 18 years old, who were diagnosed with bacteremia and nonbacteremic urinary tract infection at Sawanpracharak Hospital between January 2010 and July 2021 from 170 patient medical records in the databases. The multivariate logistic regression model was used to predict risk factors in pediatrics with bacteremia urinary tract infections. A p-value of < 0.05 was considered statistically significant.

 

Results        : The prevalence of pediatrics with bacteremia urinary tract infection was 10.6%, and 72.4% were female. The median age was 9.5 months, the median duration of fever before admission was 48 hours ,the median duration of total fever was 7 days. The maximum body temperature was 39.5oC. Four (4%) were admitted to PICU. The children with fever for more than 5 days (aOR, 13.4; 95%CI 2.77-64.96, P=0.001), recurrent urinary tract infection (aOR, 4.95; 95%CI 1.14-21.57, P=0.03), white blood cells in urine more than 100 cell/HPF (aOR, 10.35; 95%CI 1.92-55.95, P=0.01) and hematocrit less than 30% (aOR, 5.88; 95%CI 1.08-32.12, P=0.04) were statistically significant risk factors for bacteremia urinary tract infection. The mortality rate of pediatrics with bacteremia urinary tract infection was 11.1%

 

Conclusion   : This study found several risk factors for bacteremia urinary tract infection. Therefore, there should be surveillance, education, and advice to parents and medical personnel to realize the importance and proper care to reduce mortality.

 

Keywords      : Urinary tract infection, Bacteremia, Risk factors, Pediatrics

References

Karmazyn BK, Alazraki AL, Anupindi SA, Dempsey ME, Dillman JR, Dorfman SR, et al. Expert panel on pediatric imaging: ACR appropriateness criteria, urinary tract infection-child. J Am Coll Radiol 2017; 14(5S): S362-71.

Korbel L, Howell M, Spencer JD. The clinical diagnosis and management of urinary tract infections in children and adolescents. Paediatr Int Child Health 2017; 37(4): 273-9.

Millner R, Becknell B. Urinary tract infections. Pediatr Clin N Am 2019; 66: 1-13.

Crain EF, Gershel JC. Urinary tract infections in febrile infants younger than 8 weeks of age. Pediatrics 1990;86:363–7.

Pitetti RD, Choi S. Utility of blood cultures in febrile children with UTI. Am J Emerg Med 2002;20:271–4.

Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB. Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics 2011;128:595–610.

คณะกรรมการผู้เชี่ยวชาญอนุสาขาวิชาโรคไตเด็กแห่งประเทศไทยและชมรมโรคไตเด็กแห่งประเทศไทย.แนวทางเวชปฏิบัติโรคติดเชื้อทางเดินปัสสาวะในผู้ป่วยเด็กอายุ 2 เดือนถึง 5 ปี พ.ศ. 2557[อินเทอร์เน็ต]. [เข้าถึงเมื่อ 4 กันยายน 2564]. 2557 เข้าถึงได้จาก: http://www.thaipediatrics.org/Media/media-20210108072414.pdf.

Suksantilirs S, Bunjoungmanee P, Tangsathapornpong A. Bactermia in pediatric patients in Thammasat University Hospital. Thammasat Med J. 2010;10(2):144–53.

Phasuk N, Nurak A. Etiology, treatment, and outcome of children aged 3 to 36 months with fever without a source at a community hospital in Southern Thailand. J Prim Care Community Health. 2020;11:2150132720915404.

Ginsburg CM, McCracken Jr GH. Urinary tract infections in young infants. Pediatrics 1982;69:409–12.

Schnadower D, Kuppermann N, Macias CG, Freedman SB, Baskin MN, Ishimine P, et al. American Academy of Pediatrics Pediatric Emergency Medicine Collaborative Research Committee. Febrile infants with urinary tract infections at very low risk for adverse events and bacteremia. Pediatrics 2010;126:1074–83.

Averbuch D, Nir-Paz R, Tenenbaum A, Stepensky P, Brooks R, Koplewitz BZ, et al. Factors associated with bacteremia in young infants with urinary tract infection. Pediatr Infect Dis J 2014;33:571–5.

Roman HK, Chang PW, Schroeder AR. Diagnosis and management of bacteremic urinary tract infection in infants. Hosp Pediatr 2015;5:1–8.

Megged O. Bacteremic vs nonbacteremic urinary tract infection in children. Am J Emerg Med. 2017;35(1):36–8.

Yoon SH, Shin H, Lee KH, Kim MK, Kim DS, Ahn JG, et al. Predictive factors for bacteremia in febrile infants with urinary tract infection. Sci Rep. 2020;10:4469.

Ohnishi T, Mishima Y, Matsuda N, Sato D, Umino D, Yonezawa R, et al. Clinical characteristics of pediatric febrile urinary tract infection in Japan. Int J Infect Dis. 2021;104:97–101.

Published

— Updated on 2023-01-16

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How to Cite

ภู่พัฒนากุล ณัฐนรี. 2023. “Prevalence and Predictive Factor for Bacteremia in Children With Urinary Tract Infection at Sawanpracharak Hospital”. Region 3 Medical and Public Health Journal - วารสารวิชาการแพทย์และสาธารณสุข เขตสุขภาพที่ 3, January. Nakhonsawan Thailand, 13-22. https://thaidj.org/index.php/smj/article/view/12530.

Section

นิพนธ์ต้นฉบับ (Original Article)