A study of factors associated with the mortality of fungal peritonitis at Sawanpracharak Hospital
Keywords:
Fungal peritonitis, Mortality, Tenckhoff catheter removalAbstract
Objective: This study aims to investigate factors associated with mortality in patients who develop fungal peritonitis.
Methods: The study conducted a retrospective cross-sectional analysis of patients who underwent fungal peritonitis from January 1, 2007, to December 31, 2022. Data were collected from medical records in the computer system, including general information, symptoms of peritonitis, laboratory test results, treatments, and treatment outcomes.
Results: The total number of patients with fungal peritonitis among those with total Continuous Ambulatory Peritoneal Dialysis (CAPD) associated peritonitis was 44 out of 1,082 patients (4.1%). Among these, 12 patients (27.3%) died. When comparing the survival and non-survival groups, it was found that the group of patients who survived had a significantly lower proportion of patients with low serum albumin level (less than 3 grams/deciliter) compared to the non-survival group (60% vs. 100%, respectively; p-value= 0.02). Additionally, the survival group had a higher rate of catheter removal (100%) compared to the non-survival group (66.7%), which was also statistically significant (p-value< 0.01). Furthermore, patients who survived tended to have lower proportion of patients with hypotension than those who did not survive (3.2% vs. 25%, respectively; p-value= 0.06). The median survival time for patients who did not have their catheter removed was 12.0 days, significantly different from the non-survival group, where it was greater than 4,169.4 days (p-value< 0.01).
Conclusions: Fungal peritonitis is not commonly encountered but can have severe consequences leading to patient mortality. Factors associated with patient mortality include lower blood albumin levels (less than 3 grams/deciliter) and not undergoing catheter removal.
Key words: Fungal peritonitis, Mortality, Tenckhoff catheter removal
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