Prevalence of Post Stroke Dementia and Depression and Risk Factors Associated with Post Stroke Dementia at Sakon Nakhon Hospital

Abstract

             There were a few studies in post stroke dementia and depression. Also, they were not recognized and treated in general practice. The aim of this study was to study the prevalence of post stroke dementia and depression and risk factor associated with dementia after acute ischemic stroke in hospital. This prospective cohort study was conducted from January 1st to 31 October 31st, 2020 in 328 participants admitted at Sakon Nakhon Hospital. The research tools were the records of demographic and clinical characteristics, the stroke severity test; NIHSS, MRS, BI score, TMSE for cognitive test and depression screening tests (2Q 9Q). The demographic and clinical data were analyzed using the descriptive statistics. The risk factors of post stroke dementia were analyzed using the Binary logistic regression.

             The results showed that the prevalence of post stroke dementia was 26.8%. The factors significantly associated with post stroke dementia at significant level of 0.01 were age more than 60 years (AOR = 4.0, 95% CI = 2.4–2.8), elementary school education (AOR = 0.44, 95% CI = 0.20–0.74), atrial fibrillation (AOR = 6.6, 95% CI = 2.84–15.34), NIHSS score > 4 (AOR = 11.98, 95% CI = 6.1–23.2) and depression screened by 2Q test (AOR = 15.23, 95% CI = 8.44– 27.46). The prevalence of post stroke depression was 28.1%. Therefore, post stroke dementia and depression should be taken into account to rapidly treatment and prevent the incidence of these conditions.

             Keywords: Ischemic stroke, Post stroke dementia, Post stroke depression.